Frank Maldarelli, M.D., Ph.D.

Head, Clinical Retrovirology Section
Senior Investigator, CCR, NCI
Director – NIH MD/PhD Partnership Training Program

Dr. Frank Maldarelli is head of the Clinical Retrovirology Section in the NCI HIV Dynamics and Replication Program, where he leads translational studies of HIV pathogenesis with clinical protocols conducted at the NIH Clinical Center in Bethesda and laboratory studies at the NCI-Frederick campus. His laboratory studies HIV persistence during combination antiretroviral therapy, mechanisms of emergence of antiretroviral drug resistance in vivo, the genetics of HIV populations in individuals, and the spread of HIV in populations.

Dr. Maldarelli is board-certified in Internal Medicine and Infectious Diseases, and is an Attending Physician in the NIAID/CCMD HIV service. He has served on numerous oversight committees, including the NIAID Institutional Review Board (as Chair and Vice-Chair), NIH Infectious Disease Advisory Board, the Scientific Advisory Committee of the American Federation for AIDS Research, the Review Panel for the Henry M. Jackson Foundation for the Advancement of Military Medicine, and the Board of Scientific Counselors for the Food and Drug Administration. He currently chairs the NCI Center for Cancer Research Non Human Primate Scientific Review Committee. He is a faculty member of the Center for Bio-Medical Communications Infectious Disease Board Review Course and a lecturer in the Washington D.C. community outreach PACT Program. Dr. Maldarelli serves on the scientific advisory boards of the Pediatric Adolescent Virus Elimination Collaboratory (a Martin Delaney HIV Collaboratory based in Baltimore MD) and Qura Therapeutics, based in Chapel Hill, NC. His awards include the NCI leading Diversity Award in 2010 the NIH Director’s Group Award in 2015, Center for Cancer Research (CCR) Group Award in 2016, and multiple NIH Bench-to-Bedside and Intramural AIDS Targeted Antiviral Program (IATAP) awards. Dr. Maldarelli currently serves on the Editorial Boards of Journal of Virology, Pathogens, PLoS-Pathogens, Retrovirology, AIDS Research and Human Retroviruses, AIDS Research and Therapy, and Frontiers in Microbiology.

Dr. Maldarelli was born in Brooklyn, NY and grew up on Long Island. He graduated from Johns Hopkins University and from the Medical Scientist Training Program at Mount Sinai School of Medicine, where was a member of the AOA honor society. He trained in internal medicine at The Columbia-Presbyterian Medical Center in New York, and subsequently joined the Laboratory of Molecular Microbiology at the National Institute of Allergy and Infectious Diseases (NIAID) as a Medical Staff Fellow, where he worked with Klaus Strebel and Malcolm Martin studying HIV replication and pathogenesis. He completed a fellowship in Infectious Disease at NIAID before joining NCI.